Chronic, or long-lasting, inflammation is seen when longer-lived white blood cells, like macrophages, replace short-lived white blood cells, like neutrophils that are seen in an acute inflammatory response. The hallmarks of chronic inflammation are when primary inflammatory cells (such as macrophages, lymphocytes, and plasma cells) produce inflammatory cytokines, growth factors, and enzymes that contribute to ongoing tissue damage.
Kathryn Fink
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